I had to work pretty hard to do that one, but I managed it! (And I even managed to go through David Hewlett, as my plan was to prove that every actor can be linked to him).

Anthony Edwards - Will Smith (via David Hewlett)
Anthony Edwards - David Hewlett (ER)
David Hewlett - Crispin Glover (Where the Heart Is)
Crispin Glover - Mary Steenburgen (What's Eating Gilbert Grape)
Mary Steenburgen - Kevin Klein (Life As a House)
Kevin Klein - Will Smith (Wild Wild West)

*grins*